I would like to suggest that adding *something* to make looting chests actually interesing again would be a good idea.
As it stands right now I rarely even look at whats in the chest I just click loot all and move on.
For now I will limit my suggestion to Epic chests (raids and quests both). The idea could be expanded to heroic chests as well though.
Make a number of new "items" each which is akin to the Eveningstar key. That is - something with a clicky effect and a long recast timer. All of these would be minimum level 20 to use.
Effect +20 STR (of a type that stacks with everything else). Duration 10 min. Reuse time: 18 hours.
Effect: Displacement. Duration 5 mins. Reuse time 18 hours.
Effect: +20 reflex saves. Duration 5 mins. Reuse time 18 hours.
Effect. Evasion. Duration 2 mins. Reuse time 18 hours
Now add 1-3 such items to loot tables in Epic Sands, another 1-3 items to the loot tables in Epic GH, another 1-3 items to the loot tables in Demon Web quests / raids etc so that any particular item will only drop in a specific group of quests but never just in one quest.
Finally, make the drop rates tiny. This isnt something that you can just farm over a weekend or even something where you expect every player to have all or even most of these items. Make the drop rates 1:5000 for each chest in EN quests, 1:3000 for EH quests, 1:1000 for EE quests, 1:2000 for EN raids, 1:1000 for EH quests and 1:500 for EE raids. Keep in mind this is per chest and most quests/raids have multiple chests.