Okay, so lately I have been looking at runearm numbers. With all the runearm enhancements, I fire 1 shot 5x as fast as I fire a single tier 5 shot. In addition, spamming the runearm fire button I miss opportunities to shoot much less frequently due to human error. Also if a shot is a stray it's much less of a loss with a spammed shot gone astray. I had a friend time me in multiple 60 second increments and found I was firing almost exactly 10 shots in the time it takes to fire a tier 5 shot twice.
1 tier 1 shot: 4-10 (7) + 1-2 (1.5) per artificer level. Let's say you're level 28 for simplicity. 49 per shot before spellpower.
1 tier 5 shot: 8-30 (19) + 1-10 (5.5) per artificer level. 173 before spellpower.
49*5= 245 base damage.