From their twitter account: "Unrelated. Pando is not an ISP and does not handle internet routing. Only downloading for new players."
And, of course, no one will believe Turbine because they could just say something like that to cover up a mistake.
However, since the game will update and run even after removing all remnants of Pando from your system after the initial install (including all Pando dll files), it is virtually impossibly for it to be related to Pando.
The issue is related to internet traffic and routing, as was shown by multiple people with the tracert logs with connections timing out. Pando is JUST a way to share files easily (like dropbox), NOT an ISP, and not related to standard internet traffic handling in any way.