I like most of them tbh, it just depends on what character i'm playing & the concept behind them But some of the things that i particularly enjoy as twists (or potential twists once i got enuff fate points):
Rejuvenation cocoon - if you have a blue bar, take it if you have decent devotion spellpower (eg. divines, druids, pallies, rangers) then it's pretty much a no-brainer twist, especially if you've taken the empower healing feat - it's just THAT good, and only tier 1!
Meld into darkness - +100% dodge chance (bypassing normal maximums) for 15secs.. could be one of those rather neat tricks for a tank to twist & use in tricky situations.
Energy sheath - fireshield, but also for acid or lightning! ok a little situational but twisted it temporarily & it made life considerably easier when trudging through a worms gastrointestinal tract...
Boulder toss - don't be fooled by the fact its from a melee destiny, this is awesome for caster types, particularly artificers or the ol force based archmages since its physical damage which is boosted by the force/kinetic lines.. my record for this is an 8.5k crit on a helpless mob, and typically hits on a non-crit for 1100-1700... for no SP, can't really go wrong.
Wild shots - not as much damage as boulder toss, but you can throw it at a group & hit them all for 500-800 non-crit.
fey form - 7/cold iron DR & +15 universal spellpower.. pretty nice for anyone who casts spells.