Unarmed fully works with ED Combat Brute and Sense Weakness. Sense weakness probably also stacks with 10 or 20% No Mercy, but not 30%. It is likely a 10% rogue no Mercy, 20% monk no Mercy, and 30% Sense Weakness effects all stack since they are different %s and appears to be untyped.
Ninja stars in Shadowdancer maxing sneak attack / dex as a Halfling 13 rogue 6 monk 1 ranger is around 600 dps, and shurikens apply sneak immunity vulnerability debuff of SD. Sneak damage is untyped, and not increased by helpless debuff or effects. Shurikens are considered ammunition which is why all the crit profile effects don't work. However, enhancement effects (+1 dmg/hit), ammunition imbues from AA or poison quiver do work. As ammunition, you can have a weapon offhand and not be hit by TWF penalty, like a +++HAMP Kama, but also can't use shurikens with Balanced Attacks from PA for knockdown. Add an unupgraded Ring of Lies, Seal of House Avinthul, and Arrowhead to a Rad II GS Shuriken for consistent CC effects and sneak damage, which at 600 dps you will probably need.
Thrown attack speed ot 14 BAB with Whirling Wrists/Haste was 1.11 attacks/second. Quick draw/Rapid Shot will likely increase that by around 20% total (they increase different parts of the attack sequence). Whirling Wrists is a 30% increase in total shuriken throw speed, since it speeds up only part of the attack sequence.