I finaly got this one on hard solo w/o any deaths the snake boss had killed me in my last 4 attempts before this one. Its not really her thats the issue for my toon its all the trash mobs that spawn along with her. Many! Many! Balls of disco pop up on hard and your bound to fail a save roll unless you have pali type saves. Dodging the mobs, queen, balls of disco, and running through acid fogs, all while trying to pick off mobs is quite a challenge. She dose spam Acid Fog quite a lot on hard so if you dont have FoM you would need to tank her and the mobs or jump up on the chair i think. I would be interested to see how other builds deal with her and her flunkies.
This end fight is the hardest of them all(on Hard) IMO, but a lot of fun. Again, no glitch used to kill her on the chair, this was a stright up fight. Time was 46 Mins for this run.
Screen Shot: Here